‘Godzilla’ of weight-loss drugs could provide other important health benefits

Though not yet approved by any regulatory agency, Retatrutide could help improve blood sugar levels and reduce inflammation

一项大型三期试验显示，同时作用于GLP-1、GIP和胰高血糖素受体的retatrutide最高可使肥胖合并2型糖尿病者平均减重18.8%，并改善血糖、血压、血脂与炎症指标。该药尚未获批，常见不良反应为胃肠道症状，试验由生产商礼来资助。