National Geographic·· 22 d agoFeaturedRecommendation92.08
The Quest to Deliver Alzheimer's Drugs Directly to the Brain
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利用转铁蛋白受体把药物“偷渡”过血脑屏障的设想提出近四十年后,已在Hunter综合征治疗上落地,并进入阿尔茨海默病三期试验。文章梳理这一技术从受挫到突破的过程,也指出单一受体路线在副作用与精准递送上的局限。
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Source:National Geographic · nationalgeographic.com