Sleep and depression may be more intertwined than we thought

Depression tied to the body’s sleep cycle could be less responsive to antidepressants and cause more severe symptoms

一種較少為人知的抑郁亞型"晝夜節律性抑郁"可能由睡眠—覺醒周期紊亂引起，其症狀可能比其他類型更嚴重。一項針對11380名抑郁症患者的研究顯示，近四分之一符合該亞型標准，且抗抑郁藥對"夜貓子"效果更差。