‘Three-parent IVF’ was supposed to prevent mitochondrial disease. Studies are raising doubts

Scientists and ethicists are rethinking the potential risks and benefits of a technology to prevent babies from inheriting rare mitochondrial diseases.

英国已有8名通过线粒体替代技术出生的健康婴儿，但多地研究发现的“逆转”现象显示，少量母源突变线粒体可能在胚胎发育中重新占据主导。科学家与伦理学家因此重新评估该技术用于预防线粒体疾病的风险，并争论是否应先在严格试验中将其用于不孕症治疗。