‘Three-parent IVF’ was supposed to prevent mitochondrial disease. Studies are raising doubts

Scientists and ethicists are rethinking the potential risks and benefits of a technology to prevent babies from inheriting rare mitochondrial diseases.

英國已有8名通過線粒體替代技術出生的健康嬰兒，但多地研究發現的“逆轉”現象顯示，少量母源突變線粒體可能在胚胎發育中重新佔據主導。科學家與倫理學家因此重新評估該技術用於預防線粒體疾病的風險，並爭論是否應先在嚴格試驗中將其用於不孕症治療。